Rafael Nadal is through to the quarter-finals of the US Open on a day when defending ladies’ champion Naomi Osaka crashed out of the tournament (Nadal 10/11 to win US Open).

Nadal, who will be hoping to capitalise on the withdrawal of Novak Djokovic through injury, by clocking up his 19th Grand Slam title, beat Marin Cilic in four sets.

The Spaniard won the first set, before Croatian Cilic, who won the tournament back in 2014, hit back to level matters. However the Spanish ace proved to be too good in New York, eventually going through 6-3 3-6 6-1 6-2.

Nadal will now play Argentine 20th seed Diego Schwartzman in the last eight. Schwartzman made his way through to the quarters as he came from a set down to beat sixth seed Alexander Zverev 3-6 6-2 6-4 6-3.

Gael Monfils cruised past unseeded Spaniard Pablo Andujar 6-1 6-2 6-2 to go into the last eight along with Italian Matteo Berrettini, who saw off Russian Andrey Rublev 6-1 6-4 7-6 (8-6).

In the Ladies side of the draw, Osaka is out after losing 7-5 6-4 to Switzerland’s Belinda Bencic in the last 16 encounter.

The defeat means Osaka will lose her world number one ranking, with Ashleigh Barty of Australia to return to the top spot. Bencic, the 13th seed, will play Donna Vekic in the quarter-finals.

On Wednesday Roger Federer will be looking to book his place in the semi-finals of the tournament when he takes on Grigor Dimitrov (Federer 1/14, Dimitrov 13/2 – Match Betting).

Berrettini is priced at 11/8 to beat Monfils in their quarter-final, with the latter 4/7.

British number one Johanna Konta is also in action when she takes on Elina Svitolina, while Serena Williams play Qiang Wang (Svitolina 8/15, Konta 6/4 – Match Betting).

If you’re betting on Tennis, Betfred