Sevilla have the chance to reduce the deficit to table-toppers Real Madrid to just two points on Wednesday evening when they make the trip to the Mestalla to take on Valencia (Match Betting – Valencia 21/10, Draw 21/10, Sevilla 29/20).

Julen Lopetegui’s men may have been knocked out of the Copa del Rey by Real Betis last time out, losing 2-1 on the road, but they have been fantastic in the league and are unbeaten in their last six games.

Los Nervionenses have kept four clean sheets during this impressive run and have only conceded two times in total, once in the victory over Atletico Madrid and then in the draw with Barcelona.

Victory this evening would cement Sevilla’s place in second position and put them to within two points of leaders Real, who have dropped points in recent weeks to open the door for Lopetegui and Co.

Wednesday’s hosts, Valencia, are down in 10th place in the standings and they have lost their last two La Liga fixtures, going down 2-1 at home to Espanyol before losing 4-1 at Los Blancos.

Staying in Spain and there is a huge last-16 Copa del Rey clash taking place at the Anoeta Stadium at 20:00, as Real Sociedad take on Atletico Madrid for a place in the quarter-finals.

These two teams have amassed the exact same number of points (33) in the league this season, but it is the hosts that head into the contest on a three-game unbeaten run and they are 13/8 to pick up the win, while the draw is 2/1 and Atleti are 15/8.

Elsewhere, there are two Coppa Italia last-16 games taking place, starting with the 16:30 contest between Sassuolo and Cagliari before the attention turns to the 20:00 clash with Inter Milan and Empoli (Match Betting – Inter 2/11, Draw 13/2, Empoli 14/1)

The final four last-16 matches in the DFB-Pokal will also be played on Wednesday and two of those get underway at 17:30, with Hannover facing Borussia Monchengladbach and RB Leipzig taking on Hansa Rostock.

At 19:45, it’s a Berlin derby as Hertha take on Union (Match Betting – Hertha 2/1, Draw 2/1, Union 8/5), while Hoffenheim face Freiburg at the same time.

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