Week five of the NFL season will be rounded off with Indianapolis Colts at the Baltimore Ravens in Monday Night Football (Ravens 3/10, Colts 13/5 – Money Line), but ahead of that showdown, we have taken a look at which teams have been the winners and losers over the weekend.

Buffalo Bills – Winners

The statistics do not lie, with the Bills (11/2 to win Super Bowl LVI) looking the most complete team in the NFL, as they have scored more points than anyone else over the opening five weeks of the season (172) and conceded the fewest (64).

Sean McDermott’s side arguably produced their best performance to date on Sunday, as they thrashed a Patrick Mahomes-led Kansas City Chiefs 38-20 at Arrowhead Stadium.

That victory handed Buffalo revenge for their defeat to Kansas City in last season’s AFC Championship game, while it was also one of the worst regular season defeats the Chiefs have suffered in the Mahomes era.

Kansas City Chiefs – Losers

The Chiefs (7/1 to win Super Bowl LVI) have contested the last two Super Bowls, but Sunday’s loss to the Bills means they are now 2-3 for the season and sit bottom of the AFC West, while they have conceded more points than any other side in the NFL (163).

Questions are being asked of safety Daniel Sorensen, who struggled once again on Sunday after coming into the contest having allowed quarterbacks to go 14-for-17 for 170 yards on plays where he has been targeted.

Kansas City may have Mahomes, but if they want to achieve anything this season, they will have to tighten up their defence.

Arizona Cardinals – Winners

The only team in the NFL that have started the season with five wins from five are Arizona Cardinals (12/1 to win Super Bowl LVI), as they produced a gritty display in beating San Francisco 49ers 17-10 on Sunday to consolidate their position at the top of the NFC West.

Cardinals quarterback Kyler Murray outduelled his 49ers counterpart Trey Lance, although there are concerns over Murray’s fitness, as he required training staff to work on his right arm during the fourth quarter.

Murray reassured fans after the contest that he should be fine and Arizona will be hoping the same is true of center Rodney Hudson and tight end Maxx Williams, who were both forced off with injuries during the Cardinals’ latest win.

Detroit Lions – Losers

Things are just not going for the Lions (200/1 to win NFC North) and their rookie head coach Dan Campbell, as Sunday’s 19-17 loss at Minnesota Vikings leaves them 0-5 for the season.

The Lions showed plenty of heart as ever, coming from 10 points down to lead with 37 seconds remaining, but that still gave the Vikings one last chance, and Greg Joseph struck a 54-yard field goal to snatch victory away from Detroit with the last play of the game.

To make matters worse, that is the second time this season the Lions have lost to a 50-plus yard field goal with no time remaining.

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