Webb Simpson (7/2 Outright Winner) leads the field by one shot at the midway stage of the RBC Heritage event, while Englishman Matthew Fitzpatrick is just two shots off the pace.
Simpson, who finished second in this tournament back in 2013, carded two back-to-back rounds of 65 to leave him on 12-under-par.
The 2012 US Open champion went toe-to-toe with playing partner Bryson DeChambeau, who once again was pounding big drives and firing copious birdies in his second round 64.
DeChambeau (7/2) carded six birdies on the back nine to help him move to -11, along with Canada’s Corey Connors (12/1), but would have been tied for the lead if he hadn’t missed a five-footer on the last green.
Simpson doesn’t have the power of DeChambeau or some of the other US Tour stars, but he was delighted that he managed to use guile and skill to lead the way going into Saturday’s third round.
The 34-year-old said: “It’s very satisfying knowing I’m not near as long as some of these guys, and I’m able to kind of use my skills of distance control and shot shape to pick me back up when I’m 40 yards or 30 yards behind these guys.”
He went on to admit: “I would like to hit it further. I set out on a journey three years ago to get stronger, hit it further, but do it a lot slower than Bryson. But he’s made it look easy and seamless.”
Meanwhile, Fitzpatrick – currently sat 25th in the world rankings – fired a second consecutive round of 66 to leave him in a strong position going into the weekend.
The man from Sheffield (15/8 Top Five Finish) is just two back of the lead and level with American Ryan Palmer, who lost a bit of ground following his 67 on Friday.
First-round leader Ian Poulter is still inside the top-10 despite a 69, with the Ryder Cup star in a five-way tie for sixth with Brooks Koepka, Jhonattan Vegas, Abraham Ancer and Matthew NeSmith.
After a disappointing opening 72, Rory McIlroy (5/2 Top 10 Finish) was on the birdie trail on Friday to card a 65 and make sure he will be at Harbour Town Golf Links over the weekend, although he is seven shots off the lead.